Publication

    • Fractionation by Spatially Heterogeneous Diffusion: Experiments and the Two-Component Random Walk Model
      H. Kim, K. Lee (Co-first), G. Firisa, J. Lee, M. C. Choi, Y. Kim
      JACS, 146, 37 (2024) Article

      News KAIST NEWS “‘불균일 확산’ 160년 난제 풀다​“, October 2 2024

    • Water Hydrogen-Bond Mediated Layer by Layer Alignment of Lipid Rafts as a Precursor of Intermembrane Processes
      S. Lee, J. H. Bak, Y. Lee, D. Jeong, J. Lee, K. K. Lee, H. Cho, H. H. Lee, C. Hyeon, M. C. Choi
      JACS, 145, 20 (2024) Selected as Supplementary Cover of the Issue Article       Cover image

News KAIST NEWS “지질 뗏목의 원리 밝혀 질병 치료에 희소식“, June 4 2024

    • Complexes of tubulin oligomers and tau form a viscoelastic intervening network cross-bridging microtubules into bundles
      P. A. Kohl, C. Song, B J. Fletcher, R. L. Best, C Tchounwou, X. G. Garcia Arceo, P. J. Chung, H. P. Miller, L Wilson, M. C. Choi, Y. Li, S. C. Feinstein, C. R. Safinya
      Nature Communications, 15 2362 (2024) Article
    • Regulation of Interfacial Anchoring Orientation of Anisotropic Nanodumbbells
      H. Jang, C. Song, B. Kim, C. Lee, J. Lee, Y. Han, I. An, J. H. Kim, J. Nam, M. C. Choi
      ACS Macro Letters, 12 1298 (2023) Selcted as Supplementary Cover of the Issue Article Cover image 
    • Synchrotron X-ray Study of Intrinsically Disordered and Polyampholytic Tau 4RS and 4RL under Controlled Ionic Environment
      H. Cho, J. Lee, H. Nho, K. Lee, B. Gim, J Lee, J. Lee, K. Ewert, Y. Li, S. Feinstein, C. R. Safinya, K. S. Jin, M. C. Choi
      The European Physical Journal E: Festschrift in honor of Fyl Pincus, 46:73 (2023) Article
    • Ionic contrast across a lipid membrane for Debye length extension: towards an ultimate bioelectronic transducerD. Lee, W. H. Jung, S. Lee, E. S. Yu, T. Lee, J. H. Kim, H. S. Song, K. H. Lee, S. Lee, S. K. Han, M. C. Choi, D. J. Ahn, Y. S. Ryu, C. Kim
      Nature Communications, 12 3741 (2021) Article
    • 튜불린 기반 단백질 나노튜브 개발 및 항암제 전달체로의 응용
      J. Lee, M. C. Choi
      방사광 과학과 기술 (2021) Article
    • A bioinspired and hierarchically structured shape-memory material
      L. Cera, G. M. Gonzalez, Q. Liu, S. Choi, C. O. Chantre, J. Lee, R. Gabardi, M. C. Choi, K. Shin, K. K. Parker
      Nature Materials, 20 242 (2020)       Article
    • Tubulin Double Helix: Lateral and Longitudinal Curvature Changes of Tubulin Protofilament
      J. Lee, C. Song (Co-first), J. Lee, H. P. Miller, H. Cho, B. Gim, Y. Li, S. C. Feinstein, L. Wilson, C. R. Safinya, M. C. Choi
      Small, 16 2001240 (2020) Selected as Back Cover of the Issue Article  Cover image

News KAIST NEWS “단백질로 엮어낸 이중나선 개발“, Oct 30 2020

Awards  “이준철 2020 BK21 플러스 사업 우수인력 교육부장관상 수상”; “이준철 2021 춘계한국재료학회 나노 화학/바이오 재료 부문 우수 발표 논문상 수상”; “이준철  한국방사광이용자협회 대학원생 우수 논문상 수상”; “이준철 2022년도 바이오및뇌공학과 졸업식 우수 논문상 수상”; “최명철교수님 2021 국가 연구개발 우수성과 100선 선정되어 정보통신부장관상 수상”; “최명철교수 2022년 공과대학 기술혁신 우수상 수상”; “이준철 2023 한국바이오칩학회 춘계학술대회 Springer 최우수 구두발표상 수상”

    • Tubulin‐Based Nanotubes as Delivery Platform for Microtubule‐Targeting Agents
      J. Kim, J. Lee (Co-first), J. Lee, H. Keum, Y. Kim, Y. Kim, B. Yu, S. Y. Lee, J. Tanaka, S. Jon, M. C. Choi
      Advanced Materials, 32 2002902 (2020) Selected as Front Cover of the Issue Article   Cover image   

News KAIST NEWS “항암제 표적 단백질 약물전달체로 쓴다?”

    • Aggregation and Cellular Toxicity of Pathogenic or Non-pathogenic Proteins
      S. Lee, M. C. Choi, K. A. Adem, S. Luckman, T. Kim
      Scientific Reports, 10 5120 (2020) Article
    • Microtubules and Tubulin Oligomers: Shape Transitions and Assembly by Intrinsically Disordered Protein Tau and Cationic Biomolecules
      C. Safinya, P. Chung, C. Song, Y. Li, H. P. Miller, M. C. Choi, U. Raviv, K. Ewert, L. Wilson, S. Feinstein
      Langmuir, 35 15970 (2019) Article
    • Molecular Switches Regulating Assembly Transitions of Biological Molecules: Tubulin, Amylin and Lipids
      D. Jeong, S. Lee, J. Lee, H. Jang, S. Lee, M. C. Choi
      AAPPS Bulletin, (2019)
    • Inhibition of Human Amylin Aggregation and Cellular Toxicity by Lipoic Acid and Ascorbic Acid,  Molecular Pharmaceutics
      S. Azzam, H. Jang, M. C. Choi, H. Alsafar, S. Lukman, S. Lee
      Molecular Pharmaceutics, 4 15 2098 (2018) Article
    • Comparison between 102k and 20k PEO Depletants in Osmotic Pressure Measurements of Interfilament Forces in Cytoskeletal Systems
      P. Chung, C. Song, J. Deek, H. P. Miller, Y. Li, M. C. Choi, L. Wilson, S. Feisntein, C. Safinya
      ACS Macro Letters, 7 2 228 (2018) Article
    • DPPC 다중막의 수직 구조 향상을 유도하는 콜레스테롤에 의한 리플 상에서 정렬된 액체상으로의 상전이: 싱크로트론 X선 반사도 연구
      S. Lee, M. C. Choi
      방사광 과학과 기술, (2017) Article
    • Lattice Boltzmann simulations for water coalescence
      S. J. Lim, M. C. Choi, B. M. Weon, B. Gim
      Applied Physics Letters,       111 101602 (2017) Article
    • Holographic deep learning for rapid optical screening of anthrax spores
      Y. Jo, S. Park, J. Jung, J. Yoon, H. Joo, M. Kim, S. Kang, M. C. Choi, S. Y. Lee, Y. Park
      Science Advances, 3(8) e1700606 (2017)
    • Synchrotron small-angle X-ray scattering and electron microscopy characterization of structures and forces in microtubule/Tau mixtures
      P. Chung, C. Song, H. P. miller, Y. Li, U. Raviv, M. C. Choi, L. Wilson, S. C. Feinstein, C. R. Safinya
      Methods in Cell Biology, 141 155 (2017) Article
    • Vertical order of DPPC multilayer enhanced by cholesterol-induced ripple-to-liquid ordered (LO) phase transition: Synchrotron X-ray reflectivity study
      S. Lee, D. -W. Jeong, M. C. Choi
      Current Applied Physics, 17(3) 392 (2017) Article
    • Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner
      M. C. Choi, P. Chung, C. Song, H. P. Miller, E. Kiris, Y. Li, L. Wilson, S. C. Feinstein, C. R. Safinya
      Biochimica et Biophysica Acta – General Subjects, 1861, 1(A) 3456 (2017) Article
    • Enhanced stability of freestanding lipid bilayer and its stability criteria
      D. -W. Jeong, H. Jang, S. Choi, M. C. Choi
      Scientific Reports, 6 38158 (2016) Article News
    • Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
      P. Chung, C. Song, J. Deek, H. P. Miller, Y. Li, M. C. Choi, L. Wilson, S. C. Feinstein, C. R. Safinya
      Nature Communications, 7 12278 (2016) Article
    • The effect of multivalent cations and Tau on paclitaxel-stabilized microtubule assembly, disassembly, and structure
      C. R. Safinya, P. J. Chung, C. Song, Y. Li, K. Ewert, M. C. Choi
      Advances in Colloid and Interface Science, 232 9 (2016) Article
    • Direct force measurements reveal protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules
      P. J. Chung, M. C. Choi (Co-first), H. P. Miller, H. E. Feinstein, U. Raviv, L. Wilson, S. C. Feinstein, C. R. Safinya
      Proceedings of National Academy of Sciences, 112 E6416 (2015) Article  News
    • Shape-controlled percolation transition in 2D random packing of asymmetric dimers 
      Y. Han, J. Lee, S. Choi, M. C. Choi, M. W. Kim
      Europhysics Letters, 109 66002 (2015) Article
    • Fluorescence Recovery after Merging a Surfactant-Covered Droplet: A Novel Technique to Measure the Diffusion of Phospholipid Monolayers at Fluid/Fluid Interfaces
      D. Jeong, K. Kim, S. Lee, M. C. Choi, S. Choi
      Langmuir, 10(48) 14369 (2014) Article
    • Surface Charge Regulation of Carboxyl Terminated Polystyrene Latex Particles and Their Interactions at the Oil/Water Interface
      K. Kim, K. Park, G. Kim, H. Kim, M. C. Choi, S. Choi
      Langmuir, 30(41) 12164 (2014) Article
    • Surface charge effects on optical trapping of nanometer-sized lipid vesicles
      S. Park, S. Choi, C. Song, M. W. Kim, M. C. Choi
      Soft Matter, 10 8406 (2014): Cover of the issue Article   Cover image
    • Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch
      M. A. Ojeda-Lopez, D. J. Needleman(Co-first), C. Song(Co-first), A. Ginsburg, Y. Li, H. P. Miller, L. Wilson, U. Raviv, M. C. Choi, C. R. Safinya
      Nature Materials, 13 195 (2014) Article  News  Science Perspective
    • Spontaneous unilamellar polymer vesicles in aqueous solution
      T. Kim, C. Song, Y. Han, J. Jang, M. C. Choi
      Soft Matter, 10 484 (2014) Article
    • 싱크로트론 소각 X-선 산란을 이용한 단백질 나노튜브의 구조와 상호작용
      J. Lee, J. Lee, C. Song, M. C. Choi
      고분자 과학과 기술, 24(6) 596 (2013) Article
    • Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules
      D. J. Needleman, M. A. Ojeda-Lopez, U. Raviv, H. P. Miller, Y. Li, C. Song, S. C. Feinstein, L. Wilson, M. C. Choi, C. R. Safinya
      Faraday Discussions, 166 31 (2013) Article
    • Shape-induced Chiral Ordering in Two-dimensional Packing of Snowmenlike Dimeric Particles
      Y. Han, J. Lee, S. Choi, M. C. Choi, M. W. Kim
      Physical Review E, 88 032202 (2013) Article
    • High-throughput nanoscale lipid vesicle synthesis in a semicircular contraction-expansion array microchannel
      J. Lee, M. G. Lee, C Jung, Y. Park, C. Song, M. C. Choi, H. G. Park, J. Park
      BioChip Journal, 7(3) 210 (2013) Article
    • Simple Super-Resolution Live-Cell Imaging Based on Diffusion-Assisted Förster Resonance Energy Transfer
      S. Cho, J. Jang, C. Song, H. Lee, P. Ganesan, T. Y. Yoon, M. W. Kim, M. C. Choi, H. Ihee, W. D. Heo, Y. K. Park
      Scientific Reports, 3 1208 (2013) Article
    • Nanoscale Assembly in Biological Systems: From Neuronal Cytoskeletal Proteins to Curvature Stabilizing Lipids
      C. R. Safinya, U. Raviv, D. J. Needleman, A. Zidovska, M. C. Choi, M.A. Ojeda-Lopez, K. Ewert, Y. Li, H. P. Miller, J. Oquispe, B. Carragher, C. S. Potter, M. W. Kim, S. C. Feinstein, L. Wilson
      Advanced Materials, 23 2260 (2011) Article
    • Synchrotron Small Angle X-Ray Scattering Quantitatively Detects Angstrom Level Changes in the Average Radius of Taxol-Stabilized Microtubules Decorated with the Microtubule-Associated-Protein Tau
      M. C. Choi, U. Raviv, Y. Li, H. P.  Miller, D. J. Needleman, M. W. Kim, L. Wilson, S. C. Feinstein, C. R. Safinya
      Journal of Physics: Conference Series, 272 012001 (2011) Article
    • Unconventional Salt Trend from Soft to Stiff in Single Neurofilament Biopolymers
      R. Beck, J. Deek, M. C. Choi, T. Ikawa, O. Watanabe, E. Frey, P. Pincus, C. R. Safinya
      Langmuir, 26 18595 (2010) Article
    • Liquid-crystal periodic zigzags from geometrical and surface-anchoring-induced confinement: Origin and internal structure from mesoscopic scale to molecular level
      D. K. Yoon, J. Yoon, Y. H. Kim, M. C. Choi, J. Kim, O. Sakata, S. Kimura, M. W. Kim, I. Smalyukh, N. A. Clark, M. Ree, H. Jung
      Physical Review E, 82 041705 (2010) Article
    • Human Microtubule-Associated-Protein Tau Regulates the Number of Protofilaments in Microtubules: a Synchrotron X-ray Scattering Study
      M. C. Choi, U. Raviv, H. P. Miller, M. R. Gaylord, E. Kiris, D. Ventimiglia, D. J. Needleman, M. W. Kim, L. Wilson, S. C. Feinstein, and C. R. Safinya
      Biophysical Journal, 97 519 (2009): Cover of July 2 issue Article  Cover image
    • Confined Self-Assembly of Toric Focal Conic Domains (The Effects of Confined Geometry on the Feature Size of Toric Focal Conic Domains)
      Y. H. Kim, D. K. Yoon, M. C. Choi, H. S. Jeong, M. W. Kim, O. D. Lavrentovich, and H. Jung
      Langmuir, 25 1685 (2009) Article
    • Scatterless Hybrid Metal-Single-Crystal Slit For Small-Angle X-ray Scattering and High Resolution X-ray Diffraction
      Y. Li, R. Beck, M. C. Choi, and M. Divinagracia
      Journal of Applied Crystallography, 41 1134 (2008)       Article
    • Internal Structure Visualization and Lithographic Use of Periodic Toroidal Holes in Liquid Crystals
      D. K. Yoon, M. C. Choi (Co-first), Y. H. Kim, M. W. Kim, O. D. Lavrentovich, and H. Jung
      Nature Materials, 6 866 (2007) Article
    • Topographic Control of Lipid-raft Reconstitution in Model Membranes
      T. Y. Yoon, C. Jeong, S. Lee, J H Kim, M. C. Choi, S. J. Kim, M. W. Kim, and S. Lee
      Nature Materials, 5 281 (2006) Article
    • Direct Observation of Biaxial Confinement of a Semiflexible Filament in a Channel
      M. C. Choi, C. D. Santangelo, O. Pelletier, J. H. Kim, S. Y. Kwon, Z. Wen, Y. Li, P. A. Pincus, C. R. Safinya, and M. W. Kim
      Macromolecules, 38 9882 (2005) Article
    • Ordered Patterns of Liquid Crystal Toroidal Defects by Microchannel Confinement
      M. C. Choi, T. Pfohl, Z. Wen, Y. Li, M. W. Kim, J. Israelachvili, and C. R. Safinya
      Proceedings of National Academy of Sciences, 14 17340 (2004): Featured on the Cover of Dec 14 issue Article  News
    • Spontaneous Aggregation of Lipids in Supported Membranes with Geometrical Barriers
      T. Y. Yoon, C. Jeong, J. H. Kim, M. C. Choi, M, W. Kim, and S-.D. Lee
      Applied Surface Science, 238 299 (2004) Article
    • Effects of PS-PVP Diblock Copolymer Topography on the Magnetic Properties of CoCrPt Thin Films
      J. Jeong, M. C. Choi, M. W. Kim, and S. Shin
      Physica Status Solidi B, 241 1609 (2004) Article